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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sagastume, Felipe | RP | Surrey Thunderbirds | 22 | 04/07/2042 | Santo Domingo | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Sakai, Kenji | SP | Arlington Stars | 18 | 06/19/2045 | Kashiwa | JPN | Right | Right | 6' 4" | 195 lbs | - |
| Salado, Francisco | CF | Bloomington Hoosiers | 22 | 01/12/2042 | Guantanamo | CUB | Right | Right | 6' 2" | 185 lbs | - |
| Salas, Nestor | RP | River Falls Falcons | 20 | 04/28/2044 | Santo Domingo | DOM | Left | Left | 6' 0" | 170 lbs | - |
| Salazar, Antonio | SP | Royal Oak Leprechauns | 18 | 07/12/2045 | Ponce | PUR | Switch | Right | 6' 2" | 180 lbs | - |
| Salazar, David | CF | Mojave Rattlers | 22 | 08/19/2041 | Querétaro | MEX | Right | Right | 6' 2" | 175 lbs | - |
| Salazar, Jose | SP | Aiken Thoroughbreds | 21 | 02/22/2043 | San Juan | PUR | Right | Right | 6' 1" | 170 lbs | - |
| Saldivar, Marco | SP | Oak Park Architects | 20 | 09/08/2043 | San José del Progreso | MEX | Switch | Right | 6' 2" | 180 lbs | - |
| Salgado, David | RP | Martinsburg Maulers | 22 | 09/15/2041 | Coacalco | MEX | Right | Right | 6' 0" | 190 lbs | - |
| Salguero, Fernando | C | Bloomington Hoosiers | 19 | 08/03/2044 | Yauco | PUR | Right | Right | 6' 1" | 195 lbs | - |
| Salguero, Pedro | RP | San Carlos Pipers | 16 | 06/29/2047 | Corralillo | CUB | Right | Right | 6' 1" | 175 lbs | - |
| Salinas, Victor | C | Santa Clara Vampyres | 21 | 01/29/2043 | El Hatillo | VEN | Right | Right | 6' 1" | 195 lbs | - |
| Salvador, Jordan | RP | Estación Juanita Red Wings | 20 | 10/17/2043 | San Sebastian | PUR | Left | Left | 6' 2" | 180 lbs | - |
| Samudio, Jorge | LF | Media Luna Marlins | 21 | 01/19/2043 | Nuevo Casas Grandes | MEX | Left | Left | 6' 0" | 190 lbs | - |
| San Miguel, Melvin | RF | Rancho Cucamonga | 19 | 03/27/2045 | Santo Domingo | DOM | Right | Left | 6' 2" | 175 lbs | - |
| San Roman, Jorge | SP | Estación Juanita Red Wings | 20 | 01/05/2044 | Carolina | PUR | Switch | Right | 6' 9" | 200 lbs | - |
| Sanabria, Angel | 1B | Surrey Thunderbirds | 22 | 09/02/2041 | Bayamón | PUR | Right | Right | 6' 1" | 200 lbs | - |
| Sanabria, Javier | RF | Santa Clara Vampyres | 22 | 10/03/2041 | Havana | CUB | Right | Right | 6' 3" | 185 lbs | - |
| Sancen, Orlando | 3B | River Falls Falcons | 20 | 10/08/2043 | Santiago | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Sanches, Ed | 3B | Ft. Worth Werewolves | 19 | 07/04/2044 | Jaruco | CUB | Left | Right | 6' 4" | 195 lbs | - |
| Sanchez, Danny | CF | Saint John Alpines | 19 | 11/27/2044 | San Gregorio de Nigua | DOM | Right | Right | 6' 5" | 190 lbs | - |
| Sanchez, Danny | SP | Tulsa Titans | 19 | 07/27/2044 | Azcatepec | MEX | Right | Right | 6' 2" | 190 lbs | - |
| Sanchez, Jose | SP | Victory Lakes Crawfish | 19 | 06/28/2044 | Río Grande | PUR | Switch | Right | 6' 5" | 195 lbs | - |
| Sanchez, Nick | C | Rancho Cucamonga | 19 | 10/03/2044 | Totonicapan | GUA | Right | Right | 6' 0" | 195 lbs | - |
| Sanchez, Ricky | RP | San Carlos Pipers | 19 | 05/01/2045 | Caracas | VEN | Right | Right | 6' 6" | 200 lbs | - |
| Sandoval, Alex | SP | Victory Lakes Crawfish | 16 | 08/06/2047 | Santo Domingo | DOM | Left | Left | 6' 5" | 190 lbs | - |
| Sano, Sadakuno | SP | Santa Clara Vampyres | 21 | 11/14/2042 | Tono | JPN | Right | Right | 6' 6" | 205 lbs | - |
| Santa Maria, Israel | CF | Toronto Blue Jays | 20 | 11/20/2043 | El Tocuyo | VEN | Right | Right | 6' 3" | 200 lbs | - |
| Santiago, Alex | CF | San Carlos Pipers | 17 | 04/05/2047 | Caibarién | CUB | Left | Right | 6' 1" | 180 lbs | - |
| Santiago, Angelo | SP | Tulsa Titans | 21 | 12/10/2042 | Santiago de Cuba | CUB | Right | Right | 6' 3" | 195 lbs | - |
| Santiago, Carlos | CF | Royal Oak Leprechauns | 18 | 06/08/2046 | Cardenas | CUB | Right | Right | 6' 2" | 180 lbs | - |
| Santiago, Rick | C | Victoria Cougars | 21 | 02/02/2043 | Quebradillas | PUR | Right | Right | 6' 0" | 180 lbs | - |
| Santistevan, Danny | LF | Martinsburg Maulers | 21 | 04/16/2043 | Oxchuc | MEX | Right | Right | 6' 3" | 200 lbs | - |
| Santos, Gil | 2B | Ft. Worth Werewolves | 20 | 01/15/2044 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| Santos, Ignacio | CF | Victoria Cougars | 22 | 05/18/2042 | Puerto Vallarta | MEX | Right | Right | 6' 1" | 180 lbs | - |
| Sartores, Manuell | CF | Estación Juanita Red Wings | 20 | 03/15/2044 | Valle de la Pascua | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Savage, Randy | SP | Rancho Cucamonga | 19 | 06/17/2044 | Cedar Park | USA | Right | Right | 6' 1" | 180 lbs | - |
| Scheutzow, Jason | LF | Ft. Worth Werewolves | 19 | 02/17/2045 | Holland | USA | Left | Left | 6' 5" | 205 lbs | - |
| Schreiner, Mike | 3B | Oak Park Architects | 21 | 05/08/2043 | Memphis | USA | Switch | Right | 6' 4" | 200 lbs | - |
| Scott, Nate | SP | River Falls Falcons | 19 | 11/09/2044 | Portland | USA | Left | Left | 6' 5" | 195 lbs | - |
| Scott, Tom | RP | Free Agent | 30 | 12/14/2033 | Santa Rosa | USA | Right | Right | 6' 1" | 205 lbs | - |
| Segovia, Jesus | SS | Victoria Cougars | 20 | 03/15/2044 | Coamo | PUR | Right | Right | 6' 3" | 180 lbs | - |
| Segura, Andy | RP | San Carlos Pipers | 23 | 06/19/2040 | Peñuelas | PUR | Right | Left | 6' 3" | 180 lbs | - |
| Serna, Danny | SP | Saint John Alpines | 21 | 08/30/2042 | Bayamón | PUR | Right | Right | 6' 2" | 195 lbs | - |
| Serna, Gustavo | SP | Cuautitlan Izcalli Atlantics | 21 | 05/05/2043 | Colombia | CUB | Right | Right | 6' 1" | 185 lbs | - |
| Serrano, Bobby | CL | Santa Clara Vampyres | 19 | 11/27/2044 | Candelaria | CUB | Right | Right | 6' 8" | 205 lbs | - |
| Serrano, Vinny | SP | Victory Lakes Crawfish | 20 | 11/26/2043 | Comerío | PUR | Right | Right | 6' 3" | 185 lbs | - |
| Sharp, Joe | RP | Brighton Steelhounds | 20 | 08/19/2043 | Baltimore | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sierra, Tony | LF | Kingston Beats | 20 | 06/17/2043 | Canóvanas | PUR | Right | Right | 6' 5" | 195 lbs | - |
| Silva, German | CF | Toronto Blue Jays | 20 | 06/21/2043 | Benito Juarez | MEX | Right | Right | 6' 2" | 180 lbs | - |
| Silva, Julio | SP | San Carlos Pipers | 16 | 06/17/2047 | Bahía Honda | CUB | Left | Right | 5' 11" | 170 lbs | - |
| Silva, Melvin | CF | Kingston Beats | 20 | 07/18/2043 | Cayey | PUR | Right | Right | 6' 2" | 180 lbs | - |
| Sljivancanin, Gavrilo | CF | San Carlos Pipers | 19 | 07/17/2044 | Sofia | BUL | Left | Left | 6' 1" | 180 lbs | - |
| Soliz, Jose | SP | Victoria Cougars | 18 | 01/03/2046 | Chicoloapan | MEX | Left | Left | 6' 2" | 185 lbs | - |
| Soto, Esteban | SS | Victoria Cougars | 24 | 04/14/2040 | Ponce | PUR | Left | Right | 6' 1" | 195 lbs | - |
| Soto, Jose | RP | Free Agent | 27 | 02/11/2037 | Mayagüez | PUR | Left | Left | 6' 0" | 195 lbs | - |
| Soto, Mike | C | Surrey Thunderbirds | 21 | 08/10/2042 | San Luis | CUB | Left | Right | 6' 0" | 190 lbs | - |
| Starr, Tyler | RP | Victory Lakes Crawfish | 23 | 10/30/2040 | Cheswick | USA | Right | Right | 6' 1" | 200 lbs | - |
| Stefan, Mike | RF | Cuautitlan Izcalli Atlantics | 22 | 08/07/2041 | Progress Village | USA | Right | Right | 6' 0" | 190 lbs | - |
| Stewart, Adam | 1B | Santa Clara Vampyres | 22 | 09/22/2041 | Fitchburg | USA | Left | Left | 6' 6" | 200 lbs | - |
| Sullivan, Dusty | CF | San Carlos Pipers | 19 | 05/21/2045 | Bronx | USA | Switch | Right | 6' 1" | 180 lbs | - |
