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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Félix Reina# | 0.87 | 2028-2032 | |
| 2 | Ashoka Pancholi# | 1.27 | 2023-2032 | |
| 3 | Giobbe Tadiotto# | 1.71 | 2026-2032 | |
| 4 | Clarence Byrd# | 1.86 | 2021-2032 | |
| 5 | Dennis Inman | 1.87 | 2012-2022 | |
| 6 | Soleh Purbacaraka# | 1.89 | 2023-2032 | |
| 7 | Kalyanavarman Nagaraj# | 2.05 | 2022-2032 | |
| 8 | Allen Cox# | 2.25 | 2022-2032 | |
| 9 | Kunihiko Mizuno# | 2.30 | 2025-2032 | |
| 10 | John Martin | 2.33 | 2013-2027 | |
| 11 | Domingo Peña | 2.41 | 2012-2020 | |
| 12 | Jonathan Martin# | 2.48 | 2017-2031 | |
| 13 | Jon Lewis | 2.55 | 2012-2030 | |
| 14 | Bernalldo Rocchi# | 2.61 | 2023-2032 | |
| 15 | Paul Johnston# | 2.64 | 2028-2032 | |
| 15 | Christian Wallace# | 2.64 | 2022-2032 | |
| 15 | William Miller# | 2.64 | 2020-2032 | |
| 18 | Gabin Martin# | 2.65 | 2028-2032 | |
| 19 | Nate Gary# | 2.67 | 2020-2032 | |
| 20 | Rob Young | 2.68 | 2018-2029 | |
| 21 | Ed Lott | 2.74 | 2017-2029 | |
| 21 | Tokaji Goto# | 2.74 | 2017-2032 | |
| 23 | Andrés Nevárez# | 2.82 | 2017-2032 | |
| 24 | Teguh Suharto# | 2.83 | 2025-2032 | |
| 24 | Aaron Taylor | 2.83 | 2017-2030 | |
| 26 | Matt Quinlan# | 2.86 | 2022-2032 | |
| 27 | António Medrano# | 2.89 | 2023-2032 | |
| 28 | Tanner Johnson# | 2.91 | 2024-2032 | |
| 29 | Peter Miner# | 2.93 | 2025-2032 | |
| 30 | Nelson Taylor | 2.94 | 2013-2026 | |
| 31 | Anupradana Agarkar# | 3.00 | 2023-2032 | |
| 32 | Bob Ruíz# | 3.02 | 2025-2032 | |
| 33 | Carlos Núñes# | 3.03 | 2016-2032 | |
| 34 | Mike Miller | 3.09 | 2012-2023 | |
| 35 | Homer Turner | 3.10 | 2012-2020 | |
| 36 | Phoenix Smith# | 3.12 | 2022-2032 | |
| 37 | Jo-hsi Sang# | 3.14 | 2024-2032 | |
| 38 | Khurshid Durrani# | 3.18 | 2023-2032 | |
| 39 | Ross Allan# | 3.20 | 2024-2032 | |
| 40 | Adhipa Vemireddy# | 3.26 | 2024-2032 | |
| 41 | Tomás Bravo# | 3.31 | 2023-2032 | |
| 42 | Fred Butler | 3.32 | 2017-2030 | |
| 43 | Oniji Nakashima | 3.35 | 2019-2029 | |
| 44 | Rodney Armstrong | 3.38 | 2012-2024 | |
| 45 | Cohen Brouillette | 3.39 | 2015-2028 | |
| 46 | Sotatsu Hayagawa# | 3.46 | 2019-2032 | |
| 47 | Dylan Butlin# | 3.48 | 2025-2032 | |
| 48 | Joe Hardy# | 3.50 | 2023-2032 | |
| 49 | Ruberto Laranjeira | 3.52 | 2023-2031 | |
| 49 | Steve McBryde# | 3.52 | 2026-2032 | |
| 51 | Raúl Pérez | 3.55 | 2012-2021 | |
| 52 | Mitsuo Kobayashi# | 3.60 | 2028-2032 | |
| 53 | Terence McKinley | 3.61 | 2013-2023 | |
| 53 | Jack English | 3.61 | 2013-2024 | |
| 55 | Juan Luján | 3.63 | 2016-2028 | |
| 55 | Juan Mendoza# | 3.63 | 2020-2032 | |
| 57 | Ange Schmit# | 3.64 | 2024-2032 | |
| 58 | Pat Short | 3.66 | 2015-2026 | |
| 59 | Kent Williams# | 3.67 | 2027-2031 | |
| 59 | Ramón Castaneda | 3.67 | 2017-2028 | |
| 61 | Robert Long | 3.72 | 2013-2027 | |
| 62 | Oliver Romero# | 3.74 | 2023-2032 | |
| 63 | Pablo Cuevas | 3.78 | 2017-2029 | |
| 64 | Paul Barrett# | 3.80 | 2022-2032 | |
| 64 | Manuel García | 3.80 | 2022-2028 | |
| 66 | Adrien Clément# | 3.82 | 2015-2032 | |
| 67 | Kirk Snyder | 3.83 | 2017-2029 | |
| 68 | Elmer Turner# | 3.86 | 2028-2032 | |
| 69 | Na'il bin Bashshar# | 3.89 | 2023-2032 | |
| 70 | Landy Lu# | 3.91 | 2024-2032 | |
| 70 | Anthony Atkinson | 3.91 | 2013-2031 | |
| 70 | James Thompson# | 3.91 | 2025-2032 | |
| 73 | Max Grant# | 3.94 | 2022-2032 | |
| 73 | Felipe Rodríguez# | 3.94 | 2028-2032 | |
| 73 | Clayton O'Neil | 3.94 | 2016-2029 | |
| 76 | George Alexander Lewis | 3.96 | 2016-2025 | |
| 76 | Royce Butterfield | 3.96 | 2012-2019 | |
| 76 | John Bryan | 3.96 | 2015-2025 | |
| 76 | Kuniyoshi Hasegawa | 3.96 | 2021-2029 | |
| 80 | Alan Buckley | 3.97 | 2017-2029 | |
| 81 | Ray Weeks | 4.01 | 2022-2032 | |
| 82 | Iván Morales# | 4.02 | 2028-2032 | |
| 82 | Maurice Gould | 4.02 | 2012-2030 | |
| 84 | Masafumi Tamura# | 4.03 | 2024-2032 | |
| 84 | Mitsunari Kobayashi# | 4.03 | 2028-2032 | |
| 86 | Luis Vega# | 4.05 | 2019-2032 | |
| 87 | Rod Larcombe# | 4.08 | 2024-2032 | |
| 88 | Morgan Tyson# | 4.09 | 2025-2032 | |
| 89 | Brian Berry | 4.10 | 2022-2030 | |
| 90 | Luis López | 4.14 | 2014-2024 | |
| 91 | Kinnosuke Sato | 4.15 | 2016-2030 | |
| 91 | Diego Santiago# | 4.15 | 2029-2032 | |
| 91 | Brandon Wilson | 4.15 | 2012-2021 | |
| 94 | Paul Johnston | 4.20 | 2014-2026 | |
| 95 | Ze-dong Zhang# | 4.21 | 2021-2032 | |
| 96 | Jose Albertrani# | 4.22 | 2026-2032 | |
| 97 | Daryl Harrison# | 4.25 | 2027-2032 | |
| 97 | Wilson Deleón# | 4.25 | 2024-2031 | |
| 99 | Ángel Ruíz# | 4.26 | 2027-2032 | |
| 99 | Ramón Vázquez | 4.26 | 2017-2031 |
