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| Tuesday, June 15th, 2021 |
|---|
| Released 2B Tim Steele. |
| Monday, June 7th, 2021 |
|---|
| Released SP Júlio Costello. |
| SP Don Cannon joins the team. |
| SP Abel Paige joins the team. |
| SP José Chávez joins the team. |
| SP Ray Moore joins the team. |
| SP Júlio Pérez joins the team. |
| MR Paul Thompson joins the team. |
| MR Clement Sharp joins the team. |
| C Manny Marino joins the team. |
| C Jorge Esparza joins the team. |
| C Ray Jones joins the team. |
| SS Wynn Patterson joins the team. |
| LF Paul Hayes joins the team. |
| RF António Jiménez joins the team. |
| 3B Joham Espinheira joins the team. |
| SS Billy Cleary joins the team. |
| Saturday, June 5th, 2021 |
|---|
| Signed team doctor Carlos Casillas. |
| Tuesday, May 25th, 2021 |
|---|
| Signed bench coach Bennie Edwards. |
| Wednesday, May 5th, 2021 |
|---|
| Released MR Felipe Valéncia. |
| Released LF Bryant Craig. |
| Released MR Ernesto Flores. |
| Released CL Felipe Navarro. |
| Released SP Reynaldo Molina. |
| Released 1B Félix Gallegos. |
| Released C Frank Harmon. |
| Released MR Ruben Tessier. |
| Released SP Chris Johnson. |
| Bench Coach John Leiker leaves the team, his contract was not renewed. |
| Signed Hitting Coach Tokutomi Sato to a 2-year contract extension. |
| Team Trainer Randall Lee leaves the team, his contract was not renewed. |
| SP Richard Boyd joins the team. |
| 1B Juan Ríos joins the team. |
| SP Juan Cantú joins the team. |
| MR Julián Diéguez joins the team. |
| MR Júlio Cruz joins the team. |
| MR Al Southcott joins the team. |
| MR Víctor Cantú joins the team. |
| C César Cedeño joins the team. |
| C Frank Parker joins the team. |
