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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
| Sakaguchi, Hideki | SP | Grand Haven Whitecaps | 26 | 07/24/1990 | Inatsuki | JPN | Switch | Right | 5' 10" | 190 lbs | - |
| Sánchez, Jesús | 2B | Spokane Bulldogs | 20 | 07/09/1996 | Santa Clara | CUB | Switch | Right | 6' 0" | 165 lbs | - |
| Santos, Juan | C | Long Island Ducks | 28 | 05/17/1988 | Morgan | USA | Right | Right | 6' 1" | 201 lbs | - |
| Sato, Hideo | 1B | Blackpool Gamblers | 27 | 03/21/1989 | Sapporo | JPN | Right | Right | 6' 3" | 222 lbs | - |
| Sato, Hitoshi | SP | Riverside Red Bulls | 22 | 08/14/1994 | Chitose | JPN | Right | Right | 6' 5" | 230 lbs | - |
| Scarlett, Hunter | RF | Free Agent | 32 | 02/13/1984 | Saint-Jérôme | CAN | Right | Right | 6' 0" | 200 lbs | - |
| Schultz, Jerry | MR | Sandy Springs Spartans | 27 | 10/17/1989 | Lisle | USA | Switch | Right | 6' 3" | 205 lbs | - |
| Scott, Curt | LF | Free Agent | 29 | 06/10/1987 | Anaheim | USA | Left | Left | 6' 4" | 214 lbs | - |
| Scott, Ken | SS | Free Agent | 28 | 10/28/1988 | Coachella | USA | Right | Right | 6' 2" | 211 lbs | - |
| Scrymgeour, Bob | CF | Ottawa Outlaws | 25 | 03/26/1991 | Jacksonville | USA | Right | Right | 5' 10" | 191 lbs | - |
| Seki, Teika | RF | Jacksonville Hellcats | 22 | 05/09/1994 | Toyota | JPN | Right | Right | 6' 2" | 180 lbs | - |
| Sekiguchi, Yoshihito | LF | Riverside Red Bulls | 23 | 10/01/1993 | Hofu | JPN | Left | Left | 6' 3" | 160 lbs | - |
| Sepúlveda, Ricardo | MR | Riverside Red Bulls | 25 | 05/13/1991 | Santo Domingo | DOM | Left | Left | 6' 9" | 216 lbs | - |
| Shan, Li-xue | MR | Free Agent | 24 | 10/16/1992 | Lethbridge | CAN | Right | Right | 6' 5" | 230 lbs | - |
| Shannon, Tony | 2B | Free Agent | 27 | 11/10/1989 | Ellisville | USA | Right | Right | 6' 1" | 205 lbs | - |
| Shelton, Anthony | LF | Sandy Springs Spartans | 31 | 06/22/1985 | New York | USA | Right | Right | 6' 3" | 226 lbs | $800,000 |
| Sheppard, Wayne | MR | Wichita Wolverines | 26 | 11/12/1990 | Babylon | USA | Left | Left | 5' 11" | 195 lbs | - |
| Shoemaker, Howard | 2B | Sandy Springs Spartans | 25 | 08/29/1991 | Lubbock | USA | Switch | Right | 6' 3" | 180 lbs | - |
| Silva, Jesús | 2B | Free Agent | 21 | 03/25/1995 | Zaza del Medio | CUB | Right | Right | 6' 0" | 190 lbs | - |
| Silva, Ramón | C | Spokane Bulldogs | 20 | 06/26/1996 | Santo Domingo | DOM | Right | Right | 5' 11" | 205 lbs | - |
| Simmons, Joe | C | Cincinnati Snaps | 24 | 10/27/1992 | Grosse Pointe Park | USA | Right | Right | 6' 1" | 200 lbs | - |
| Simons, Michael | 2B | Carson City Mustang | 25 | 10/14/1991 | Los Angeles | USA | Right | Right | 6' 1" | 186 lbs | - |
| Simpson, James | RF | Blackpool Gamblers | 24 | 01/09/1992 | New York | USA | Right | Right | 6' 3" | 195 lbs | - |
| Simpson, William | 3B | Free Agent | 27 | 08/07/1989 | Westminster | USA | Right | Right | 5' 8" | 195 lbs | - |
| Singleton, Chris | SS | Wichita Wolverines | 25 | 09/10/1991 | Canton | USA | Right | Right | 6' 2" | 220 lbs | - |
| Smith, Damian | SP | Free Agent | 28 | 06/25/1988 | Cape Girardeau | USA | Left | Left | 5' 8" | 188 lbs | - |
| Smith, Dan | LF | Free Agent | 27 | 10/09/1989 | Palm Beach | USA | Switch | Right | 6' 0" | 195 lbs | - |
| Smith, Dirk | CF | Free Agent | 30 | 12/01/1986 | Gilbert | USA | Right | Right | 6' 4" | 210 lbs | - |
| Smith, Jacques | RF | Madison Beehive | 21 | 05/15/1995 | Guelph | CAN | Right | Right | 6' 3" | 215 lbs | - |
| Smith, Jeffrey | C | Asheville Tourists | 22 | 09/05/1994 | Phoenix | USA | Right | Right | 6' 0" | 195 lbs | - |
| Smith, Jim | 1B | Newark Jail Birds | 25 | 07/17/1991 | Cincinnati | USA | Right | Right | 5' 11" | 190 lbs | - |
| Smith, John | MR | Ottawa Outlaws | 25 | 02/19/1991 | Gainesville | USA | Right | Right | 6' 6" | 215 lbs | - |
| Smith, Tom | MR | Long Island Ducks | 25 | 04/03/1991 | Green Valley | USA | Right | Left | 6' 4" | 225 lbs | - |
| Snow, Gene | 3B | Free Agent | 27 | 04/22/1989 | Deerfield | USA | Right | Right | 6' 0" | 205 lbs | - |
| Snyder, Daniel | CF | Free Agent | 22 | 03/30/1994 | Houston | USA | Left | Left | 6' 0" | 165 lbs | - |
| Sonnino, Domeneco | MR | Phoenix Lights | 21 | 11/25/1995 | El Limón | VEN | Left | Left | 6' 4" | 245 lbs | - |
| Soto, Roberto | LF | Free Agent | 23 | 09/25/1993 | Aguascalientes | MEX | Right | Left | 6' 2" | 188 lbs | - |
| Sparks, Jack | 1B | Madison Beehive | 24 | 09/22/1992 | Houston | USA | Right | Left | 6' 5" | 205 lbs | - |
| Spencer, Monte | 1B | Free Agent | 26 | 02/10/1990 | Los Angeles | USA | Right | Right | 6' 1" | 173 lbs | - |
| Spencer, Scott | MR | Madison Beehive | 26 | 07/28/1990 | Charlotte | USA | Right | Right | 6' 7" | 213 lbs | - |
| Spencer, Tom | SS | Free Agent | 28 | 06/15/1988 | Tulsa | USA | Right | Right | 6' 0" | 208 lbs | - |
| Spivey, Gerald | SP | New York Ninjas | 25 | 08/02/1991 | Potomac | USA | Right | Right | 6' 0" | 205 lbs | - |
| Springer, Peter | MR | Madison Beehive | 25 | 01/13/1991 | Mansfield | USA | Switch | Right | 6' 1" | 195 lbs | - |
| St. John, Andrew | SP | Wichita Wolverines | 25 | 09/19/1991 | Jacksonville | USA | Right | Right | 6' 4" | 200 lbs | - |
| Stafford, William | CF | Rock River Rats | 25 | 04/09/1991 | Beaufort | USA | Right | Right | 6' 0" | 215 lbs | - |
| Starratt, Dave | LF | Grand Haven Whitecaps | 22 | 08/24/1994 | Saint-Jean-sur-Richelieu | CAN | Right | Right | 6' 4" | 200 lbs | - |
| Stephens, Chris | RF | Free Agent | 31 | 06/14/1985 | Beaumont | USA | Right | Right | 6' 3" | 168 lbs | - |
| Stephens, Tom | 2B | Free Agent | 23 | 09/09/1993 | Biloxi | USA | Switch | Right | 5' 11" | 195 lbs | - |
| Stephenson, Brenden | MR | Blackpool Gamblers | 25 | 10/02/1991 | Butler | USA | Switch | Right | 6' 0" | 185 lbs | - |
| Sterling, Gregg | C | Free Agent | 24 | 05/03/1992 | Dover | USA | Right | Right | 6' 1" | 220 lbs | - |
| Stevens, Tim | 1B | Free Agent | 24 | 11/08/1992 | Stuarts Draft | USA | Left | Left | 5' 11" | 180 lbs | - |
| Stevens, Tim | SP | New York Ninjas | 29 | 04/18/1987 | Lebanon | USA | Left | Left | 5' 11" | 182 lbs | - |
| Stevenson, Timothy | MR | Ottawa Outlaws | 27 | 09/04/1989 | Seattle | USA | Right | Right | 5' 10" | 190 lbs | - |
| Stewart, Alex | 2B | Wichita Wolverines | 24 | 07/15/1992 | Shoreview | USA | Switch | Right | 6' 1" | 190 lbs | - |
| Stewart, Brian | SP | Spokane Bulldogs | 25 | 12/22/1991 | Phoenix | USA | Right | Right | 6' 2" | 215 lbs | - |
| Stone, Albert | SP | Madison Beehive | 23 | 05/16/1993 | New Bedford | USA | Left | Left | 5' 10" | 220 lbs | - |
| Stone, Eric | 3B | Long Island Ducks | 25 | 03/27/1991 | New York | USA | Right | Right | 6' 0" | 165 lbs | - |
| Stone, Garland | 2B | Free Agent | 24 | 09/29/1992 | Millen | USA | Right | Right | 5' 8" | 190 lbs | - |
| Stone, Millard | SP | Silicon Valley Hackers | 24 | 08/31/1992 | West Hartford | USA | Right | Left | 6' 2" | 235 lbs | - |
| Strickland, Wayne | C | Wichita Wolverines | 26 | 07/06/1990 | Charles City | USA | Switch | Right | 6' 2" | 225 lbs | - |
| Stuart, Dave | SP | Wichita Wolverines | 27 | 04/25/1989 | Pittsburg | USA | Left | Left | 6' 3" | 198 lbs | - |
| Su-Tu, Hsiao-lou | C | Spokane Bulldogs | 21 | 02/11/1995 | Caloundra | AUS | Right | Right | 5' 9" | 185 lbs | - |
| Sullivan, Alex | 1B | Silicon Valley Hackers | 25 | 04/27/1991 | Wilmington | USA | Right | Right | 6' 0" | 200 lbs | - |
| Sullivan, Eric | CF | Anniston Cougars | 23 | 11/27/1993 | West Lafayette | USA | Left | Left | 6' 0" | 170 lbs | - |
| Sullivan, Robby | 2B | Carson City Mustang | 27 | 09/19/1989 | Newburyport | USA | Right | Right | 5' 10" | 190 lbs | - |
| Sumita, Nobuhisa | CL | Riverside Red Bulls | 21 | 07/03/1995 | Shimada | JPN | Left | Left | 6' 1" | 260 lbs | - |
| Sutton, Jeremy | CF | Frisco Rams | 23 | 10/28/1993 | Sydney Mines | CAN | Left | Left | 5' 10" | 180 lbs | - |
| Suzuki, Keitaro | CF | Riverside Red Bulls | 26 | 04/15/1990 | Inami | JPN | Right | Right | 5' 10" | 185 lbs | - |
| Suzuki, Robun | LF | Ottawa Outlaws | 21 | 03/24/1995 | Yotsukaido | JPN | Left | Right | 6' 3" | 185 lbs | - |
| Svarudze, Jafar | MR | Ottawa Outlaws | 27 | 08/18/1989 | Hinsdale | USA | Left | Left | 5' 11" | 212 lbs | - |
| Sweetapple, Jeremy | SS | Silicon Valley Hackers | 23 | 01/16/1993 | Toronto | CAN | Switch | Right | 6' 4" | 210 lbs | - |
