| | | Monday, October 31st, 2016 |
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| Signed Manager Damian Connor to a 5-year contract extension. | | Signed Bench Coach Pedro Hesía to a 4-year contract extension. |
| Sunday, October 30th, 2016 |
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| Signed Hitting Coach Amaro Vagos to a 3-year contract extension. | | Signed Pitching Coach Oliver Washington to a 5-year contract extension. |
| Saturday, October 29th, 2016 |
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| Placed MR Glen Rush on the active roster. | | Activated MR Glen Rush from the disabled list. |
| Monday, September 26th, 2016 |
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| Placed MR Glen Rush on the 14-day disabled list, retroactive to 09/20/2016. |
| Friday, August 19th, 2016 |
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| Signed 3B Howard Lawrence to a 5-year contract extension worth a total of $47,400,000. |
| Monday, July 11th, 2016 |
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| Placed SP Reynaldo Martínez on the 14-day disabled list, retroactive to 07/10/2016. | | Placed CL Dave Walton on the active roster. |
| Monday, June 13th, 2016 |
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| CL Dave Walton was designated for assignment and placed on waivers. | | Placed MR Glen Rush on the active roster. | | Activated MR Glen Rush from the disabled list. |
| Monday, April 11th, 2016 |
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| Placed RF Ricardo Marquis on the 14-day disabled list, retroactive to 04/05/2016. | | Purchased the contract of CF Hubert Munoz from Triple A Joplin. |
| Monday, March 21st, 2016 |
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| Signed free agent RF Ricardo Marquis to a 2-year contract worth a total of $25,000,000. |
| Saturday, March 12th, 2016 |
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| Placed SP Pepe López on the 60-day disabled list. |
| Sunday, December 6th, 2015 |
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| Signed Alan Buckley to a minor league contract with a signing bonus of $200,000. |
| Wednesday, December 2nd, 2015 |
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| Signed Scouting Director Emílio Parra to a 5-year contract extension. |
| Monday, November 30th, 2015 |
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| Signed Michael Burton to a minor league contract with a signing bonus of $160,000. | | Signed Larry Strafford to a minor league contract with a signing bonus of $250,000. |
| Saturday, November 28th, 2015 |
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| Signed Peter Coleman to a minor league contract with a signing bonus of $200,000. |
| Thursday, November 26th, 2015 |
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| Signed Donald Hoover to a minor league contract with a signing bonus of $150,000. |
| Tuesday, November 24th, 2015 |
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| CL Millard Moore received a 1-year contract through automatic renewal worth a total of $500,000. | | CF Wilson Thompson received a 1-year contract through automatic renewal worth a total of $500,000. | | DH Ricardo Marquis becomes a free-agent. | | SP John Bryan received a 1-year contract through automatic renewal worth a total of $500,000. | | 2B James Riley received a 1-year contract through automatic renewal worth a total of $500,000. | | MR Kevin Rutledge received a 1-year contract through automatic renewal worth a total of $500,000. | | CF Claude Morin received a 1-year contract through automatic renewal worth a total of $500,000. | | C Jesús Delgado received a 1-year contract through automatic renewal worth a total of $500,000. | | RF John Byford received a 1-year contract through automatic renewal worth a total of $500,000. | | RF Eugene White received a 1-year contract through automatic renewal worth a total of $500,000. | | 3B Lucas Smith received a 1-year contract through automatic renewal worth a total of $500,000. | | LF Tim Tuttle received a 1-year contract through automatic renewal worth a total of $500,000. | | 3B William Simpson received a 1-year contract through automatic renewal worth a total of $500,000. |
| Saturday, November 21st, 2015 |
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| SP Rodney Armstrong received a 1-year contract through arbitration worth a total of $4,725,000. | | MR Jon Lewis received a 1-year contract through arbitration worth a total of $2,000,000. | | 2B Armando Rodríguez received a 1-year contract through arbitration worth a total of $7,500,000. | | MR Robert Cates received a 1-year contract through arbitration worth a total of $800,000. | | SP Fabrizio Palgani was not offered arbitration, becomes a free agent. | | MR Jorge Magana received a 1-year contract through arbitration worth a total of $800,000. | | 3B Howard Lawrence received a 1-year contract through arbitration worth a total of $4,750,000. | | SP Martin Merritt received a 1-year contract through arbitration worth a total of $3,178,500. | | SP José Ramírez received a 1-year contract through arbitration worth a total of $800,000. |
| Thursday, November 5th, 2015 |
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| Signed team doctor Jim Connor to a 4-year, $800,000 per year contract. |
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