| Saturday, November 7th, 2015 |
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| Drafted 3B Jon Hughes in the 2015 first-year player draft (Round 6, Pick 17, 150th overall pick). | | Released CF Misao Kokawa. | | Drafted 3B Lorenzo Constant in the 2015 first-year player draft (Round 7, Pick 17, 174th overall pick). | | Drafted SS Vincente Ventura in the 2015 first-year player draft (Round 8, Pick 17, 198th overall pick). | | Drafted 3B Wyatt Lewis in the 2015 first-year player draft (Round 9, Pick 17, 222nd overall pick). | | Drafted 2B Carl Edmonds in the 2015 first-year player draft (Round 10, Pick 17, 246th overall pick). | | Drafted 3B Roy Nichols in the 2015 first-year player draft (Round 11, Pick 17, 270th overall pick). | | Drafted 3B Christian Chevalier in the 2015 first-year player draft (Round 12, Pick 17, 294th overall pick). |
| Wednesday, November 4th, 2015 |
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| Signed hitting coach Jeremy Fox. |
| Thursday, October 22nd, 2015 |
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| Manager Chris Carpenter leaves the team, his contract was not renewed. | | Hitting Coach Juan Jose Cavazos leaves the team, his contract was not renewed. |
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