| Thursday, December 31st, 2015 |
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| Signed free agent LF Juan Ramírez to a 5-year contract worth a total of $100,000,000. |
| Monday, December 14th, 2015 |
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| Placed MR Mal Meade on the 60-day disabled list. | | Placed 1B Eric McSwan on the active roster. | | C Garrett Wilson was designated for assignment and placed on waivers. | | SP Dean Pride was designated for assignment and placed on waivers. |
| Friday, December 4th, 2015 |
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| Signed free agent 1B Eric McSwan to a 5-year contract worth a total of $100,000,000. |
| Thursday, December 3rd, 2015 |
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| Signed CL David Reynolds to a 6-year contract extension worth a total of $75,500,000. |
| Tuesday, November 24th, 2015 |
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| RF Patrice Delhaye received a 1-year contract through automatic renewal worth a total of $500,000. | | SS Tim McCreary received a 1-year contract through automatic renewal worth a total of $500,000. | | 3B Eduardo Gómez becomes a free-agent. | | SP Scott Wilson received a 1-year contract through automatic renewal worth a total of $500,000. | | LF Tom Maddox received a 1-year contract through automatic renewal worth a total of $500,000. | | SP Tim Berry received a 1-year contract through automatic renewal worth a total of $500,000. | | LF Tommy Harris becomes a free-agent. | | SP Dean Pride received a 1-year contract through automatic renewal worth a total of $500,000. | | MR Arturo Cruz received a 1-year contract through automatic renewal worth a total of $500,000. | | MR Rhett Combs received a 1-year contract through automatic renewal worth a total of $500,000. | | MR Allen Robbins becomes a free-agent. | | SP Thomas White becomes a free-agent. | | RF Jordan Lewis received a 1-year contract through automatic renewal worth a total of $500,000. | | SP Chris Phillips received a 1-year contract through automatic renewal worth a total of $500,000. | | MR Kurt Taylor received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Paul Durden received a 1-year contract through automatic renewal worth a total of $500,000. | | 1B Shannon Gray received a 1-year contract through automatic renewal worth a total of $500,000. | | CF Harold Poole received a 1-year contract through automatic renewal worth a total of $500,000. | | C Garrett Wilson received a 1-year contract through automatic renewal worth a total of $500,000. |
| Saturday, November 21st, 2015 |
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| CF Daniel Rodríguez received a 1-year contract through arbitration worth a total of $1,600,000. | | SP Manuel López received a 1-year contract through arbitration worth a total of $800,000. |
| Friday, November 20th, 2015 |
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| Signed Sean Dunbar to a minor league contract with a signing bonus of $720,000. |
| Thursday, November 19th, 2015 |
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| Signed Allan Jackson to a minor league contract with a signing bonus of $420,000. |
| Sunday, November 15th, 2015 |
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| Signed Tim O'Herlihy to a minor league contract with a signing bonus of $160,000. |
| Thursday, November 12th, 2015 |
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| Signed Tetsuo Chikuda to a minor league contract with a signing bonus of $140,000. |
| Wednesday, November 11th, 2015 |
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| Signed Kevin Landry to a minor league contract with a signing bonus of $2,500,000. |
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