| | | Monday, September 24th, 2012 | | Signed 1B George Sanders to a 4-year contract extension worth a total of $70,260,000. | | Placed CF Edgar Johnson on the active roster. | | Activated CF Edgar Johnson from the disabled list. |
| Friday, September 21st, 2012 | | Placed 2B Michael McFarland on the 14-day disabled list, retroactive to 09/20/2012. |
| Friday, September 14th, 2012 | | Placed SS Dane Moore on the 14-day disabled list, retroactive to 09/12/2012. | | Placed CF Edgar Johnson on the 14-day disabled list, retroactive to 09/09/2012. | | Placed 2B Derrick Meadows on the active roster. | | Activated 2B Derrick Meadows from the disabled list. |
| Friday, September 7th, 2012 | | Placed 3B Salvador Salgado on the 14-day disabled list, retroactive to 09/05/2012. | | Purchased the contract of SP Al Boyd from Triple A Albuquerque. |
| Monday, July 2nd, 2012 | | Placed CF Cromawn Faherty on the 14-day disabled list, retroactive to 06/30/2012. | | Placed RF Steve Frend on the active roster. | | Activated RF Steve Frend from the disabled list. |
| Monday, June 18th, 2012 | | Placed RF Steve Frend on the 14-day disabled list, retroactive to 06/14/2012. | | Placed CF Edgar Johnson on the active roster. | | Activated CF Edgar Johnson from the disabled list. |
| Tuesday, June 12th, 2012 | | Signed CF Edgar Johnson to a 4-year contract extension worth a total of $44,000,000. |
| Friday, February 17th, 2012 | | Signed hitting coach Ray Colvin to a 2-year, $170,000 per year contract. |
| Tuesday, January 31st, 2012 | | Signed team doctor Matt Watts to a 5-year, $520,000 per year contract. |
| Monday, January 30th, 2012 | | Signed manager Marc Johnston to a 3-year, $750,000 per year contract. |
| Friday, January 20th, 2012 | | Signed pitching coach Dan Parent to a 5-year, $230,000 per year contract. |
| Wednesday, January 4th, 2012 | | Signed bench coach Carlos Brown to a 5-year, $770,000 per year contract. |
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