| | | Friday, August 31st, 2012 | | Signed CL Joe Lowry to a 3-year contract extension worth a total of $18,000,000. |
| Tuesday, August 28th, 2012 | | Signed Hitting Coach John Eaton to a 3-year contract extension. |
| Sunday, August 26th, 2012 | | Signed CF Gordon Thornton to a 5-year contract extension worth a total of $104,000,000. |
| Monday, May 28th, 2012 | | Placed MR Martín Torres on the 14-day disabled list, retroactive to 05/27/2012. | | Purchased the contract of SP Marcus Barber from Triple A El Paso. |
| Saturday, April 7th, 2012 | | Signed MR Donald Henderson to a 2-year contract extension worth a total of $1,900,000. |
| Friday, April 6th, 2012 | | Signed MR James Malise to a 2-year contract extension worth a total of $5,600,000. | | Signed 1B Robert Carr to a 3-year contract extension worth a total of $7,500,000. |
| Saturday, March 3rd, 2012 | | Purchased the contract of LF Dan Allen from Double A Ottawa. |
| Thursday, February 23rd, 2012 | | Signed team doctor Brad Russell to a 3-year, $600,000 per year contract. |
| Wednesday, February 22nd, 2012 | | Signed bench coach Alex Woods to a 3-year, $700,000 per year contract. |
| Saturday, February 18th, 2012 | | Signed pitching coach José Gutiérrez to a 4-year, $300,000 per year contract. | | Signed hitting coach John Eaton to a 1-year, $240,000 per year contract. |
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