| | | Thursday, December 20th, 2012 | | Signed free agent MR Brad Austin to a 4-year contract worth a total of $40,000,000. |
| Tuesday, December 18th, 2012 | | Signed free agent MR Jim Dorsey to a 4-year contract worth a total of $38,000,000. |
| Monday, December 17th, 2012 | | Drafted SP Toshiki Koda in the 2012 first-year player draft (Round 1, Pick 7, 7th overall pick). | | Drafted C Seitaro Uenohara in the 2012 first-year player draft (Round 2, Pick 7, 31st overall pick). | | Drafted SS Éric Chapelle in the 2012 first-year player draft (Round 3, Pick 7, 55th overall pick). | | Drafted CL Conrad Orton in the 2012 first-year player draft (Round 4, Pick 7, 79th overall pick). | | Drafted MR Juan Lejeune in the 2012 first-year player draft (Round 5, Pick 7, 103rd overall pick). | | Drafted CL Jeremiah Barton in the 2012 first-year player draft (Round 6, Pick 7, 127th overall pick). | | Drafted MR Ken Ives in the 2012 first-year player draft (Round 7, Pick 7, 151st overall pick). | | Drafted SP Hugo Racine in the 2012 first-year player draft (Round 8, Pick 7, 175th overall pick). | | Drafted SP Pat Short in the 2012 first-year player draft (Round 9, Pick 7, 199th overall pick). | | Drafted CL Jeff Ramey in the 2012 first-year player draft (Round 10, Pick 7, 223rd overall pick). | | Drafted MR Hugh Shnairson in the 2012 first-year player draft (Round 11, Pick 7, 247th overall pick). | | Drafted SP Miguel Gonzáles in the 2012 first-year player draft (Round 12, Pick 7, 271st overall pick). |
| Wednesday, December 5th, 2012 | | Signed C Ronnie Wells to a 4-year contract extension worth a total of $28,480,000. |
| Wednesday, November 21st, 2012 | | RF Mike Bergeron received a 1-year contract through automatic renewal worth a total of $6,000,000. | | 3B Michael Brown received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Mike Miller received a 1-year contract through automatic renewal worth a total of $500,000. | | RF Orlando Carranzo received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Jerome Burnett received a 1-year contract through automatic renewal worth a total of $510,000. | | MR Ambrosio Cuco received a 1-year contract through automatic renewal worth a total of $510,000. | | CF Jesús González received a 1-year contract through automatic renewal worth a total of $510,000. | | SP William Nolan received a 1-year contract through automatic renewal worth a total of $500,000. | | SS Dylan Foster received a 1-year contract through automatic renewal worth a total of $510,000. | | 1B Joe Sharpe received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Royce Butterfield received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Francis Baker received a 1-year contract through automatic renewal worth a total of $510,000. | | C David Rivera received a 1-year contract through automatic renewal worth a total of $510,000. | | LF Andrew Padgett received a 1-year contract through automatic renewal worth a total of $510,000. | | SP Paul Green received a 1-year contract through automatic renewal worth a total of $500,000. | | MR José López received a 1-year contract through automatic renewal worth a total of $500,000. | | SS John House received a 1-year contract through automatic renewal worth a total of $510,000. | | C Michael Kent becomes a free-agent. | | 3B Kajoshaj Kadare becomes a free-agent. |
| Sunday, November 18th, 2012 | | SP Joe Erickson becomes a free-agent. | | MR Chris Knight becomes a free-agent. | | MR Wesley Oliver received a 1-year contract through arbitration worth a total of $935,000. | | SP Chris Johnson received a 1-year contract through arbitration worth a total of $1,320,000. |
| Monday, November 12th, 2012 | | Placed SP Jerome Burnett on the 60-day disabled list. |
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