| | | Sunday, December 23rd, 2012 | | Signed free agent SS Doug Smith to a 4-year contract worth a total of $5,400,000. |
| Thursday, December 20th, 2012 | | Signed CF Chris Stephens to a 3-year contract extension worth a total of $2,550,000. | | Signed 2B Jeff Morgan to a 3-year contract extension worth a total of $2,370,000. |
| Wednesday, December 19th, 2012 | | Signed C Ed Griffin to a minor league contract extension. | | Signed SP Jesús Ruíz to a minor league contract extension. | | Signed CF Anthony Lewis to a 4-year contract extension worth a total of $31,960,000. | | Signed MR Tony Flores to a minor league contract extension. | | Signed Scouting Director Alfonso Gil to a 5-year contract extension. |
| Monday, December 17th, 2012 | | Drafted SP Calvin Stackhouse in the 2012 first-year player draft (Round 1, Pick 17, 17th overall pick). | | Drafted CL Naofumi Kouda in the 2012 first-year player draft (Round 2, Pick 17, 41st overall pick). | | Drafted SP Vaughan Ambrose in the 2012 first-year player draft (Round 3, Pick 17, 65th overall pick). | | Drafted SP Yoritomo Ito in the 2012 first-year player draft (Round 4, Pick 17, 89th overall pick). | | Drafted SP Kenzo Takashita in the 2012 first-year player draft (Round 5, Pick 17, 113rd overall pick). | | Drafted SP Jotaro Fukuda in the 2012 first-year player draft (Round 6, Pick 17, 137th overall pick). | | Drafted SP Isei Azuma in the 2012 first-year player draft (Round 7, Pick 17, 161st overall pick). | | Drafted MR Jean-Baptiste Andrieu in the 2012 first-year player draft (Round 8, Pick 17, 185th overall pick). | | Drafted SP Stephen Joseph in the 2012 first-year player draft (Round 9, Pick 17, 209th overall pick). | | Drafted SP Naizen Ogawa in the 2012 first-year player draft (Round 10, Pick 17, 233rd overall pick). | | Drafted SP José Bustamante in the 2012 first-year player draft (Round 11, Pick 17, 257th overall pick). | | Drafted MR Morihiro Sato in the 2012 first-year player draft (Round 12, Pick 17, 281st overall pick). |
| Monday, December 10th, 2012 | | Signed free agent SP Alberto Ramírez to a minor league contract. |
| Thursday, December 6th, 2012 | | Signed team doctor Dale Martin to a 1-year, $450,000 per year contract. |
| Wednesday, November 21st, 2012 | | LF Anthony Shelton received a 1-year contract through automatic renewal worth a total of $510,000. | | MR Ernie Kuhn received a 1-year contract through automatic renewal worth a total of $510,000. | | MR Keith Thompson received a 1-year contract through automatic renewal worth a total of $510,000. | | 1B Don Strickland received a 1-year contract through automatic renewal worth a total of $510,000. | | MR Brad Austin becomes a free-agent. | | C Jorge Rodríguez received a 1-year contract through automatic renewal worth a total of $510,000. | | 2B Tom Hunter received a 1-year contract through automatic renewal worth a total of $510,000. |
| Sunday, November 18th, 2012 | | Signed free agent MR Brian Sanderson to a minor league contract. |
| Monday, November 12th, 2012 | | Signed free agent MR Edward Brown to a minor league contract. |
| Wednesday, November 7th, 2012 | | Signed C Ed Griffin to a minor league contract extension. |
| Thursday, November 1st, 2012 | | Signed CF Chris Stephens to a 1-year contract extension worth a total of $750,000. | | Signed SP Jesús Ruíz to a minor league contract extension. | | Signed 2B Jeff Morgan to a 1-year contract extension worth a total of $820,000. | | Signed MR Earnest Saunders to a minor league contract extension. | | Signed SP Jesse George to a 2-year contract extension worth a total of $10,000,000. | | Signed MR Tony Flores to a minor league contract extension. |
| Sunday, October 28th, 2012 | | Team Trainer Dale Martin leaves the team, his contract was not renewed. |
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