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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
| O'Connor, Charles | MR | Montgomery Mountain Cats | 36 | 11/24/1976 | Algonquin | USA | Right | Right | 5' 11" | 207 lbs | $6,000,000 |
| O'Day, Craig | CF | Montgomery Mountain Cats | 31 | 02/07/1981 | Staten Island | USA | Left | Left | 6' 0" | 211 lbs | $12,500,000 |
| O'Donnell, Steve | SS | Los Angeles Evil Empire | 33 | 08/15/1979 | Carrollton | USA | Right | Right | 5' 10" | 202 lbs | $10,500,000 |
| O'Keggan, Brian | SP | San Francisco Earthquakes | 27 | 08/01/1985 | Eaton Rapids | USA | Right | Right | 5' 7" | 190 lbs | $750,000 |
| O'Macken, Jeff | SP | Free Agent | 30 | 02/12/1982 | Montecito | USA | Right | Right | 6' 0" | 218 lbs | - |
| O'Neal, Joe | CF | Nottinghamshire Outlaws | 22 | 05/31/1990 | Upton | USA | Left | Left | 6' 0" | 185 lbs | $510,000 |
| O'Neill, Jayson | C | South Carolina Bombers | 25 | 04/04/1987 | Spanish Springs | USA | Right | Right | 6' 2" | 195 lbs | $510,000 |
| O'Neil, Robert | CF | South Carolina Bombers | 26 | 01/25/1986 | Rock Island | USA | Left | Left | 6' 2" | 232 lbs | - |
| O'Reilly, Foster | C | New York Mafia | 24 | 04/21/1988 | Millersville | USA | Switch | Right | 6' 0" | 205 lbs | - |
| O'Reilly, Gene | C | Montreal Bandits | 26 | 02/26/1986 | West Des Moines | USA | Left | Right | 6' 4" | 225 lbs | $510,000 |
| O'Rorke, Dave | SP | Free Agent | 33 | 11/09/1979 | New York | USA | Right | Right | 6' 1" | 190 lbs | - |
| Oditón, León | C | Seattle Sasquatch | 25 | 05/29/1987 | Burlington | USA | Switch | Right | 6' 0" | 197 lbs | $510,000 |
| Okada, Tsumemasa | MR | Minnesota Berserkers | 34 | 02/04/1978 | Ube | JPN | Switch | Left | 6' 0" | 206 lbs | $3,800,000 |
| Olsen, Marshall | MR | Kansas City Tornadoes | 36 | 05/12/1976 | Brooklyn | USA | Left | Left | 6' 1" | 202 lbs | $6,500,000 |
| Olson, Dave | LF | New York Mafia | 27 | 07/25/1985 | New York | USA | Right | Right | 6' 0" | 210 lbs | $510,000 |
| Olson, Mike | C | Free Agent | 35 | 11/17/1977 | Pittsburgh | USA | Right | Right | 5' 11" | 218 lbs | - |
| Orozco, Cristián | LF | Boston Cardinals | 31 | 05/22/1981 | Havana | CUB | Switch | Right | 6' 1" | 199 lbs | $750,000 |
| Orr, Julian | 2B | Free Agent | 32 | 09/10/1980 | San Pablo | USA | Right | Right | 6' 0" | 207 lbs | - |
| Ortega, Ramiro | CL | Carolina Crush | 22 | 05/26/1990 | Netcong | USA | Right | Right | 6' 0" | 175 lbs | $510,000 |
| Ortíz, Iván | LF | Jacksonville Jacks | 26 | 01/23/1986 | Maracaibo | VEN | Right | Right | 5' 11" | 188 lbs | $510,000 |
| Ortíz, José | 2B | Las Vegas Jokers | 25 | 08/24/1987 | Delicias | MEX | Right | Right | 6' 3" | 160 lbs | $510,000 |
| Ortíz, Miguel Angel | 1B | San Diego Tomcats | 30 | 03/22/1982 | Santo Domingo | DOM | Right | Right | 6' 8" | 212 lbs | $17,000,000 |
| Ortíz, Santiago | SP | Free Agent | 25 | 04/20/1987 | Belle Glade | USA | Left | Right | 6' 4" | 230 lbs | - |
| Owens, Tom | MR | Dallas Texans | 22 | 05/24/1990 | Billerica | USA | Right | Right | 6' 0" | 210 lbs | $510,000 |
